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The combination of a levonorgestrel-releasing intrauterine device (LNG-IUD), metformin, and liraglutide has been shown to safely and effectively improve endometrial hyperplasia in obese patients, as well as promote the regression of early-stage endometrial cancer [41]

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WMD = 0.21 kg/m 2 , 95% CI 1.31 to 0.88, P = 0.7, I 2 = 0.0%)

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